By Charles M. Poser
This illustrated pocketbook offers an simply obtainable precis of key matters with regards to diagnosing a number of sclerosis and dealing with sufferers at assorted levels of the disease.
summary: This illustrated pocketbook offers an simply available precis of key concerns with regards to diagnosing a number of sclerosis and coping with sufferers at various levels of the ailment
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Additional info for An illustrated pocketbook of multiple sclerosis
It is somewhat difficult to appreciate why the last category was included. For the first time, primary progressive MS (PPMS) is carefully characterized, the problem of pseudoexacerbations is mentioned, and the diagnostic value of brain stem auditory and somatosensory evoked potentials is questioned. Symptoms are not acceptable. Regarding MRI, the criteria lack a qualitative dimension which is so important in distinguishing between MS and disseminated encephalomyelitis, but those for spinal cord lesions and for dissemination in time are most useful.
When symptomatic myelin edema occurs during an exacerbation, remission may result in either complete or partial recovery, depending upon functional restoration of the required number of fibers, or in a permanent deficit, as a result of myelinoclasia. From Poser, 1993; reproduced with permission of Elsevier Science BV Diagnosis Diagnosticcriteria The diagnosis of MS is a clinical exercise based on the characteristic dissemination of the lesions in both space and time. This principle applies to the overwhelming majority of cases.
1994; reproduced with permission of the Radiological Society of America AN ILLUSTRATED POCKETBOOK OF MULTIPLE SCLEROSIS 27 Figure 19 Brain section in Baló’s disease showing (upper) concentric demyelination in the right centrum semiovale. High-power view of the same area (lower) shows alternating bands of normal myelin and remyelmation. Weigert stains. Shiraki, University of Tokyo, Japan 28 AN ILLUSTRATED POCKETBOOK OF MULTIPLE SCLEROSIS Figure 20 Gross specimen of brain from a patient with Schilder’s myelinoclastic diffuse sclerosis shows large bilateral areas of demyelination Figure 21 Celloidin section of brain from a patient with Schilder’s myelinoclastic diffuse sclerosis shows a large plaque occupying most of the centrum semiovale.
An illustrated pocketbook of multiple sclerosis by Charles M. Poser